After multiple dosing, lisinopril displays an effective half-life of 12 hours.

“If blood stress is not controlled regarding Zestril alone, a low dose of a diuretic might be included (eg, hydrochlorothiazide, 12.5 mg).”

Toprol-XL (metoprolol) is a beta-blocker that influences the heart as well as circulation (blood circulation through arteries and also capillaries).